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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
TMEM48
All Species:
6.36
Human Site:
S474
Identified Species:
14
UniProt:
Q9BTX1
Number Species:
10
Phosphosite Substitution
Charge Score:
-0.2
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9BTX1
NP_060557.2
674
76305
S474
T
C
Y
G
S
P
Q
S
P
Q
L
I
R
R
G
Chimpanzee
Pan troglodytes
XP_513417
776
87618
S576
T
C
Y
G
S
P
Q
S
P
Q
L
I
R
R
G
Rhesus Macaque
Macaca mulatta
XP_001091911
530
59703
L338
A
L
Q
D
L
M
L
L
S
Q
Y
S
P
S
R
Dog
Lupus familis
Cat
Felis silvestris
Mouse
Mus musculus
Q8VCB1
673
75391
Q475
S
G
S
P
Q
S
P
Q
L
I
R
R
G
P
R
Rat
Rattus norvegicus
Q6AXN4
673
75694
Q475
C
G
S
P
Q
S
P
Q
L
V
R
R
G
P
R
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001518195
431
47121
T237
E
R
R
G
K
M
P
T
L
P
V
P
W
A
V
Chicken
Gallus gallus
XP_001235442
684
77153
L485
H
G
S
V
Q
S
P
L
V
M
R
R
G
P
K
Frog
Xenopus laevis
Q6AX31
660
74320
R468
V
Q
S
P
Q
V
T
R
R
G
A
K
L
W
T
Zebra Danio
Brachydanio rerio
Q7SZC5
671
74423
Q471
S
P
W
F
G
T
V
Q
S
P
H
I
M
R
R
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q9VCG4
578
65368
T386
S
L
P
M
P
K
I
T
E
S
L
T
T
S
L
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_784037
756
85199
K563
D
S
Y
G
V
V
Q
K
S
L
P
D
I
L
T
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
86
76.4
N.A.
N.A.
87
86.9
N.A.
20.4
67.8
56.8
53.5
N.A.
22.7
N.A.
N.A.
28.1
Protein Similarity:
100
86.2
77.3
N.A.
N.A.
92.1
92.5
N.A.
33.5
79.3
72.4
72.2
N.A.
43.4
N.A.
N.A.
45.3
P-Site Identity:
100
100
6.6
N.A.
N.A.
0
0
N.A.
6.6
0
0
13.3
N.A.
6.6
N.A.
N.A.
20
P-Site Similarity:
100
100
6.6
N.A.
N.A.
6.6
0
N.A.
20
0
0
26.6
N.A.
20
N.A.
N.A.
20
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
10
0
0
0
0
0
0
0
0
0
10
0
0
10
0
% A
% Cys:
10
19
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
10
0
0
10
0
0
0
0
0
0
0
10
0
0
0
% D
% Glu:
10
0
0
0
0
0
0
0
10
0
0
0
0
0
0
% E
% Phe:
0
0
0
10
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
28
0
37
10
0
0
0
0
10
0
0
28
0
19
% G
% His:
10
0
0
0
0
0
0
0
0
0
10
0
0
0
0
% H
% Ile:
0
0
0
0
0
0
10
0
0
10
0
28
10
0
0
% I
% Lys:
0
0
0
0
10
10
0
10
0
0
0
10
0
0
10
% K
% Leu:
0
19
0
0
10
0
10
19
28
10
28
0
10
10
10
% L
% Met:
0
0
0
10
0
19
0
0
0
10
0
0
10
0
0
% M
% Asn:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% N
% Pro:
0
10
10
28
10
19
37
0
19
19
10
10
10
28
0
% P
% Gln:
0
10
10
0
37
0
28
28
0
28
0
0
0
0
0
% Q
% Arg:
0
10
10
0
0
0
0
10
10
0
28
28
19
28
37
% R
% Ser:
28
10
37
0
19
28
0
19
28
10
0
10
0
19
0
% S
% Thr:
19
0
0
0
0
10
10
19
0
0
0
10
10
0
19
% T
% Val:
10
0
0
10
10
19
10
0
10
10
10
0
0
0
10
% V
% Trp:
0
0
10
0
0
0
0
0
0
0
0
0
10
10
0
% W
% Tyr:
0
0
28
0
0
0
0
0
0
0
10
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _